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differential hematology systemic algorithm causes generalized leukemia management pruritus agglutinin anemia behcet clinical cll cold cryoglobulinemia cryoglobulins erythematosus hemolytic lupus
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... leukocytoclastic vasculitis ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Secondary ... : • Behcet Disease ... • Cogan syndrome ... Vasculitis #skin ... #dermatology #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... syndrome Psychiatric ... Pruritus #primary #secondary ... #generalized #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... syndrome Psychiatric ... #Pruritus #secondary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... #rheumatology # ... classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ) • Cutaneous Lesions ... Ischemia, Leukemia, Lymphoma ... Recurrent and chronic ... signs #symptoms #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous ... #types #classification ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... #Syndromes #diagnosis ... #hematology #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Secondary form ... Diagnosis: • Dry ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Rheumatology #
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