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differential hematology algorithm systemic allergy causes generalized immunology leukemia pruritus agglutinin anemia cold common cutaneous cvid dermatologic eosinophilia erythematosus gpa
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... - Goodpasture syndrome ... - Schnitzler syndrome ... - Sjögren syndrome ... #Diagnosis #Rheumatology
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
hypereosinophilic syndrome ... Hyper-lgE (Job) syndrome ... , T-cell leuk/lymphoma ... , B-cell lymphomas ... , Behcet disease
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD ... : • Behcet Disease ... • Cogan syndrome ... #skin #dermatology ... #rheumatology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #workup #oncology ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... syndrome Psychiatric ... Pruritus #primary #secondary ... #generalized #dermatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... syndrome (Clinical ... adenopathy (PFAPA) syndrome ... #Syndrome #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... #Syndromes #diagnosis ... #hematology #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... • Goodpasture syndrome ... • Angiocentric lymphoma ... #rash #diagnosis ... #rheumatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... syndrome Psychiatric ... #Pruritus #secondary
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