10 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Algorithm - Systemic ... Creatinine & BUN: • Chronic ... Differential: • Lymphoma ... Myelodisplastic syndrome ... #generalized #dermatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Syndrome (CAS): ... Diagnosis: • hemolytic ... #disease #hemolytic ... #anemia #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... #oncology #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Skin Lesion - Differential ... Diagnosis Algorithm ... Differential: • Lymphoma ... Myelodisplastic syndrome ... #secondary #systemic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , deficiency anemia ... , Vasculitides, ... IBD, Celiac disease ... #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Granulomatous lymphocytic ... • Nodules • Lymphoid ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Pruritis ... nodosum • Immune hemolytic ... anemia • Pain ... number of sites of disease ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... #Rheumatology