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diagnosis management anthracycline behcets cardiotoxicity chronic cll cyp3a4 diuresis diuretics doac druginduced excretion hemeonc hemophagocytic her2 hlh inducers interactions leukemia
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Topical steroids • Prevention ... Azathioprine and/or TNF-α inhibitors ... azathioprine • TNF-α inhibitors ... #management #pharmacology ... #rheumatology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy # ... Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
benefit of immediate chemotherapy ... for low-risk disease ... (Bruton kinase inhibitor ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... Anti-infectious, chemotherapy ... Anti-IFN-y and JAK inhibitors ... #summary #rheumatology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Kidney stones caused ... nocturnal enuresis • Prevention ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... methyltransferase inhibitors ... ) • Intensive chemotherapy ... Syndromes #diagnosis #hematology ... #oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Anthracyclines cause ... ) and initiate treatment ... Cardiotoxicity #cardiology ... #oncology #pharmacology ... #toxicity #chemotherapy
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