16 results
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Conditioning regimen Signs ... /Symptoms: Typically ... EBV viral load, signs ... Diagnosis and classification ... oncology #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... /SYMPTOMS: • CENTRAL ... Signs and symptoms ... /or cerebellar symptoms ... sclerosis #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... of end organ damage ... TLS #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
with visceral organ ... Symptoms: • The ... Organ involvement ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... and damage of organs ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
inflammation of multiple organs ... meningitis), MCC CNS symptoms ... Behcet disease) Differential ... #diagnosis #management ... #signs #symptoms
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
emergency: permanent organ ... hyperthermia crisis (late sign ... • Serotonin syndrome ... #Hyperthermia #Differential ... Checklist #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... with multiple organ ... Lymphohistiocytosis #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... unless severe APLS, organ ... APML #diagnosis #management