15 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... indicated • For organ-specific ... signs or symptoms ... #Algorithm #Differential ... #diagnosis #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... Conditioning regimen Signs ... EBV viral load, signs ... Lymphoproliferative #Disorders ... oncology #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... with multiple organ ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... of end organ damage ... TLS #diagnosis #management ... #hematology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
life • M=F Symptoms ... and Signs: 50% ... changes, and other organ ... and signs: • ... leukocytosis, psychiatric disorders
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... infiltrate any organ ... lymphoproliferative disorders ... workup #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... ) - Internal organs ... Episcleritis Signs ... and Symptoms: ... Syndrome #diagnosis #dermatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... and damage of organs ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management