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diagnosis oncology treatment syndrome workup arthritis dermatology classification disorders hemophagocytic hlh joint lymphohistiocytosis neurology pain sclerosis systemic vasculitis algorithm als
Manifestations of IgG4-related disease by organ system. The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... indicated • For organ-specific ... signs or symptoms ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin and internal organs ... skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Conditioning regimen Signs ... , unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... oncology #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
(aPL) 30-45% Differential ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
with visceral organ ... Symptoms: • The ... Edema in 70% of cases ... Organ involvement ... Resolution > 15 days Differentials
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... bile ducts Differential ... Lymphoma and solid organ
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... of end organ damage ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
inflammation of multiple organs ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
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