9 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... of end organ damage ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
: • Tumor-like ... Signs and symptoms ... Multiple Sclerosis Treatment ... sclerosis #diagnosis #management ... #neurology #treatment
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
herniation or tumour ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
life • M=F Symptoms ... and Signs: 50% ... changes, and other organ ... Less common symptoms ... and signs: •
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... Psychiatric symptoms ... nonimmune hemolysis MSK ... vasculitis Treatment ... #VitaminC #AscorbicAcid
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... and damage of organs ... anterior/posterior MSK ... #Signs #Symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
inflammation of multiple organs ... Arthritis, AS Treatment ... interferon alfa, or tumor ... Syndrome #diagnosis #management ... #signs #symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... and/or symptoms ... Enhancement - TM and tumor ... Transverse Myelitis Treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ ... Persistent fever, organ ... Presentation • Common Signs ... and Symptoms: ... Pathophysiology