19 results
diagnosis management hematology oncology activetb disease hemophagocytic hlh infectiousdiseases latenttb lymphohistiocytosis tb thrombocytopenia tuberculosis acute agglutinin algorithm anemia apml cancer
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... weeks without infection ... microglobulin Treatment ... Leukemia #diagnosis #workup
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... • Clinical: fever ... Unknown cause Treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... with multiple organ ... following: • Fever ... #hematology
Disseminated Gonococcal Infection - Diagnosis and Management Summary Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
the preferred test ... typically part of the workup ... • Test all patients ... : • Fever, chills ... Purulent Arthritis Syndrome
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Symptoms: High fevers ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculin skin test ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Headache (45%) • Fever ... Labs: • CD4+ T-cell ... ) Treatment:
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculin skin test ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... petechiae) • Frequent infections ... • Parvovirus infection ... agents given to organ ... Workup: • Complete
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