27 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... : Chronic infections
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... SLE], AOSD) • Infection ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Headache (45%) • Fever ... ) Treatment: ... ART to slow HIV disease
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Symptoms: High fevers ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... with multiple organ ... following: • Fever ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
from a visceral organ ... Calcium oxalate Infectious ... Acute or chronic infections ... Joint #Pain #MSK #rheumatology ... #approach #workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... cells can indicate disease ... microglobulin Treatment ... Leukemia #diagnosis #workup
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... Connective tissue diseases ... • Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... mycobacteria Treatment