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diagnosis management hematology oncology activetb tb tuberculosis activation anesthesia anesthesiology apml causes checklist chronic classification cll differential differentiation hemophagocytic hlh
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculin skin test ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • Fever ... Tuberculin skin test ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... lab signs of end organ ... damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
The Stages of Syphilis Primary Syphilis - The chancre lesion is the hallmark of primary syphilis.
Without treatment ... common internal organ ... and nephrotic syndrome ... roots, causing a syndrome ... GrepMed Recommended Text
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
emergency: permanent organ ... Treatment depends ... Actively maintained fever ... • Serotonin syndrome ... Diagnosis #Management #Workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... infiltrate any organ ... microglobulin Treatment ... Leukemia #diagnosis #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... unless severe APLS, organ
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... with multiple organ ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... agents given to organ ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology
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