24 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement • Other organ ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement • Other organ ... Can involve any organ ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
Tuberculin Skin Test ... Threshold for treatment ... individual with active TB ... consistent with old TB ... disease • HIV
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
for Celiac Disease ... patients with celiac disease ... value for celiac disease ... Reflects response to treatment ... #Diagnosis #Workup
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... Infection and Disease ... disease) Indications ... (+) screening test ... #IDSA #Prevention
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... IGRA/QuantiFERON-TB ... intermediate risk of disease ... age ACTIVE TB ... Testing #Diagnosis #Workup
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB)
 •
IDSA - Clinical ... Individualized Treatment ... disease who are ... MDRTB #management #Treatment ... pharmacology #dosing #idsa
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
e.g. cirrhosis + TB ... of underlying disease ... bilirubin 2) Routine tests ... 3) Optional tests ... Jcortesizaguirr #Ascites #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematology for workup ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Chronic infections, TB
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... with response to treatment ... specific laboratory tests ... IgG4 #Related #Disease ... management #phenotypes #workup