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diagnosis oncology syndrome tuberculosis activetb disease hivaids infections latenttb pharmacology prevention apml chagas chronic classification cll cmv cytomegalovirus dermatology differentiation
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Tuberculosis Treatment ... Initiating Treatment ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
: • Fever • Weight ... Tuberculosis Treatment ... Initiating Treatment ... #Diagnosis #Management ... #Treatment #ActiveTB
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
IDSA Recommendations ... (+) screening test ... #IDSA #Prevention ... #Treatment #management ... #opportunistic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... • SJS/TEN • Acute ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
specific laboratory tests ... hypergammaglobulinemia, ↑ acute ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, acute ... lab signs of end organ ... TLS #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... with multiple organ ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... weeks incubation Acute ... mild (malaise, fever ... Confirmatory Tests ... - check Acute
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