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hematology management syndrome chronic cll differential differentiation immune inflammatory iris leukemia lymphocytic mds myelodysplasia myelodysplastic reconstitution syndromes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... coagulopathy, RRT/IMV ... #hematology #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
granulomatous nephritis, fevers ... - Pneumonitis (fever ... leukoencephalopathy (PML ... keratitis, iritis • CMV ... Fever, chills, lack
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... infiltrate any organ ... microglobulin Treatment ... #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... agents given to organ ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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