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differential barre causes algorithm cord disorders gbs gitelman guillainbarre hypokalemia ms multiple myopathy neuromuscular sams sclerosis spinal spinalcord statin toxicity
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
syndrome, Mononeuritis ... Phrenic nerve injury ... Lambert Eaton Syndrome ... , Myasthenia Gravis ... #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... syndrome - Miller ... #Gravis #diagnosis ... #management #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
• Muscle weakness ... • Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Miller Fisher Syndrome ... #Barre #Syndrome ... #diagnosis #management ... #treatment #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... - Compartment syndrome ... Neuroleptic malignant syndrome ... syndrome • Myoglobinuria ... #treatment #nephrology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
syndrome (GBS), ... antisynthetase syndrome ... Lambert-Eaton myasthenic ... syndrome (LEMS) ... #management #treatment
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... but 5% have anti—muscle-specific ... and in myasthenic ... #Gravis #diagnosis ... #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... signs below the ... - Transverse myelitis ... MCTD, Sjogren syndrome ... #neurology #differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... cauda equina TREATMENT ... #Barre #Syndrome ... #diagnosis #management ... #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Signs and symptoms ... #management #neurology ... #treatment #MS
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