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diagnosis management fungal infections candida algorithm antifungal auris betadglucan bronchiectasis candidemia candidiasis celiac cglabrata dermatitis differential disease falsepositives fever fungemia
Invasive fungal infections: Morphology, Risk Factors, Disease Characteristics, Diagnostic Tools, First-Line Treatment Aspergillus, Mucorales, P. Jiroveci, Cryptococcus,
Invasive fungal ... Tools, First-Line Treatment ... Aspergillus, Mucorales ... , Fusarium #Invasive ... Fungal #Infections #InfectousDiseases
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... Diagnosis and Testing ... neutropenia (performs best ... this morphology Treatment ... #fungal #infectiousdiseases
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
Invasive Candidiasis ... Non-culture-based tests ... • Molecular Tests ... susceptibility testing ... Line Targeted Treatment
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing ... use: Candida, Aspergillus ... the use of this test ... colonization vs invasive ... Galactomannan #Fungal #Testing
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
adults • Blood tests ... Pulmonary function tests ... Sweat chloride test ... aeruginosa • Aspergillus ... mycobacteria Treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
IPVDs Diagnostic Testing ... oximetry - Non-invasive ... 10 minutes of rest ... ) on room air Treatment ... diagnosis #management #treatment
Fever of Unknown Origin (FUO) Diagnostic Algorithm STEP 1 Perform a comprehensive history and complete physical examination. STEP
Apply appropriate invasive ... tuberculosis skin test ... positive first-tier testing ... diagnostic testing ... Diagnosis #Algorithm #infectiousdiseases
Candida Glabrata Species of Candida Most Commonly Isolated in Bloodstream Infections • Symptomatic mucosal infection is detected
is common with invasive ... Treatment: • Exhibits ... candidemias or invasive ... susceptibility testing ... fungemia #management #infectiousdiseases
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
material) > local invasion ... disease: • Optimal treatment ... moderate Tx in setting ... Fusarium #Infections #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Urinary antigen testing ... ASPERGILLOSIS • Aspergillus ... Ampho resistant) Invasive ... of 30% to 40% Invasive ... ) #Mycoses #InfectiousDiseases
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