3 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Renal Failure Treatment ... 500 mg QD until normal ... fluid overload, PCC
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
JAK2 mutation OR Abnormally ... incidentally via CBC ... transformation into AML ... • Treatment algorithms ... #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Diagnosis: On the CBC ... are usually near-normal ... transformation into MDS or AML ... • Treatment is ... • Treatment algorithms