7 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... kwburak #LFTs #Elevated ... #hepatology #LiverFunctionTests
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... • Fatigue PBC ... #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... specificity to elevated ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... disease US — Normal ... Bile Ducts • PSC ... Others #LFTs #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... > 5 or elevated ... Renal Failure Treatment ... 500 mg QD until normal ... fluid overload, PCC
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Criteria: • Elevated ... JAK2 mutation OR Abnormally ... incidentally via CBC ... • Treatment algorithms ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
reported (eg AIH-PBC ... IgG typically elevated ... upper limit of normal ... regarding need for treatment ... Diagnosis #Management #Hepatology