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apml causes differential elevated hematology liverenzymes liverfunctiontests management oncology syndrome transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Algorithm Severe ... disease US — Normal ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Triggers: ATRA treatment ... Renal Failure Treatment ... 500 mg QD until normal ... fluid overload, PCC
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