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diagnosis oncology leukemia algorithm chronic cll hemeonc hemophagocytic hlh lymphocytic lymphohistiocytosis rheumatology acquired activation acute aml anemia apl aplastic cancer
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
granules, and Auer ... KyleBradleyMD #Auer ... #APML #Pathology ... #Hematology #Clinical ... #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
• Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... peripheral blood smear ... Age: 50-60 • Auer ... • Peripheral smear ... #Leukemia #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... disorders • Shear ... vonWillebrand #Syndrome ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Triggers: ATRA treatment ... Renal Failure Treatment ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... transformation) Treatment ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... factor (GCSF) treatments ... Peripheral blood smear ... marrow studies Treatment ... #diagnosis #hematology
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