14 results
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Based Approach to Hyponatremia ... #Hyponatremia #Algorithm ... #Pathophysiology ... Nephrology #UOsm #Osmolality
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... retention 1) Serum Osmolarity ... 2) Urine Osmolarity ... Rachel Stern MD #Hyponatremia
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Thiazide induced Hyponatremia ... - Pathophysiology ... independent / ADH ... Thiazide #induced #Hyponatremia ... #Pathophysiology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... and Treatment Hyponatremia ... Treatment of hyponatremia ... of symptomatic (seizures ... @EmmGeezee #Hyponatremia
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... urea causes the hyponatremia ... True hyponatremia ... #hyponatremia #ADH
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Hyponatremia Diagnostic ... 1) Check serum osmolality ... 3) ADH Dependent ... @kidney_boy #Hyponatremia ... #differential #hyponatremia
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Hypovolaemia → ADH ... SaltWasting #SIADH #Pathophysiology ... diagnosis #nephrology #hyponatremia
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Saline: • If Urine osmolality ... antagonists: • Blocks ADH ... SIADH #Management #hyponatremia
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
-> Withdrawal seizure ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
NS • If Urine osmolality ... vaptans) • Blocks ADH ... SIADH #Management #hyponatremia