3 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... endothelial damage • Induce ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... #management #hematology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
organizing pneumonia, ARDS ... toxicity (e.g., acute ... respiratory distress syndrome ... failure - Infectious ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... baseline or both • Rule ... leukoencephalopathy (PML ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management