21 results
Cushing Syndrome - Hypercortisolism Differential Diagnosis Algorithm

#Cushings #Syndrome #Differential #Diagnosis #Algorithm #disease #endocrinology #Hypercortisolism
Cushing Syndrome ... Diagnosis Algorithm #Cushings ... #Syndrome #Differential ... Algorithm #disease #endocrinology
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm
Exogenous (ACTH-independent)
Endogenous
 • ACTH-dependent:
    - ACTH-secreting
Hypercortisolism (Cushing ... syndrome) - Simplified ... pituitary adenoma (Cushing ... #syndrome #Differential ... Diagnosis #Algorithm #endocrinology
Cushing Syndrome - Likelihood Ratios of Physical Exam Findings
Moon facies LR +1.6
Central obesity LR +3.0
Generalized obesity
Cushing Syndrome ... SatyaPatelMD #Cushings ... #Syndrome #Likelihood ... PhysicalExam #diagnosis #endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... dysfunction (males) #Cushings ... #Syndrome #Signs ... Symptoms #diagnosis #endocrinology
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Neoplasias (MEN syndromes ... • Possible ZE syndrome ... Acromegaly • Cushing ... syndrome • ... #Differential #Endocrinology
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Cushing Syndrome ... : • Suspected Cushing ... syndrome (central ... #Syndrome #diagnosis ... #algorithm #endocrinology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Carbenoxolone, SAME, Cushing ... Syndrome • HTN ... diuretics, Bartter syndrome ... , Gitelman syndrom ... Algorithm #causes #potassium
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
hemianopsia IGF-1 Overproduction ... Carpal Tunnel Syndrome ... GrowthHormone #GH #Excess #Overproduction ... signs #symptoms #endocrinology
Hirsutism - Differential Diagnosis
Defined as excessive dark, coarse, male-pattern hair growth
Hirsutism causes in premenopausal women:
 •
steroids • Rare: Cushing's ... Syndrome, Acromegaly ... Adrenal, Ovary • Cushing's ... Syndrome, Acromegaly ... Differential #Diagnosis #endocrinology
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Polycystic Ovarian Syndrome ... Hyperplasia • Cushing's ... Syndrome Tumor ... Paraneoplastic Syndrome ... Diagnosis #Algorithm #endocrinology