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diagnosis hematology oncology anemia aplastic febrile hemophagocytic hlh lp lymphohistiocytosis pediatrics risk stepbystep stratification
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... serious bacterial infections ... #Diagnosis #Management ... #Pediatrics #Peds ... #LP #Antibiotics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Syndrome in APML ... Subacute-Acute: • Common: fever ... Differential Diagnosis: Infection ... #Syndrome #APML ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... frequently affects infants ... following: • Fever ... rapidly, and empiric antibiotic ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... Presentation: • Fever ... - β-lactam antibiotics ... aplastic anemia Treatment ... #diagnosis #management
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