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diagnosis hematology infant lp oncology pediatrics risk stepbystep stratification anemia aplastic bloodstream catheter crbsi differential differentiation ebm hemophagocytic hlh immune
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
- Management Algorithm ... Antibiotic Management ... • Persistent fever ... Hernodynamically stable after treatment ... #Management #Algorithm
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... serious bacterial infections ... #Pediatrics #Peds ... #Febrile #Infant ... #LP #Antibiotics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Differential Diagnosis: Infection ... #management #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... treatment. http ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... acute or subacute febrile ... following: • Fever ... rapidly, and empiric antibiotic ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... Presentation: • Fever ... - β-lactam antibiotics ... aplastic anemia Treatment ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... ischemia, bowel infarction ... : - If febrile ... TLS #diagnosis #management ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... - Overview of IRIS ... leukoencephalopathy (PML ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
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