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hematology oncology activation anemia aplastic lymphohistiocytosis macrophage mas
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... rapidly, and empiric antibiotic ... #management #treatment ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Syndrome in APML ... Subacute-Acute: • Common: fever ... : Infection (sepsis ... #Syndrome #APML ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... - β-lactam antibiotics ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... #diagnosis #management
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