11 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... heart block • Sjogren ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Overview What ... (renal potassium ... syndrome, Renal ... Rhabdomyolysis Treatment ... #management #pathophysiology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... GQ1b IgG Antibody associated ... #management #treatment ... #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
heart failure, neurologic ... Hypertension associated ... Pregnancy-associated ... Neurologic disorders ... , and Guillain-Barre
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Heme associated ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... or compartment syndrome ... Heme associated ... Treatment of underlying ... #nephrology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Overview Epidemiology ... Primary form: not associated ... Adenocarcinoma Treatment ... #Syndrome #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis Overview ... Associated with: ... Autoimmune: thyroid, Sjogren ... syndrome, rheumatoid ... diagnosis #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
(PRES) Overview ... may precede the neurologic ... fluctuations PRES-Associated ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE), Sjögren ... ’s syndrome, ANCA-associated ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology