7 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
of breath • Neurologic ... viscosity > 4 cP • Associated ... Hyperphosphatemia • Hyperkalemia ... Hyperuricemia • Acute renal ... failure • Hypocalcemia
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... Heme associated ... Dialysis for severe hyperkalemia
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Overview What ... (renal potassium ... , Renal tubular ... Rhabdomyolysis Treatment ... #management #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... or compartment syndrome ... Heme associated ... Treatment of underlying ... #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Anaphylaxis, Acute Renal ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
(PRES) Overview ... may precede the neurologic ... fluctuations PRES-Associated ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Overview Epidemiology ... Primary form: not associated ... Distal (Type I) renal ... Adenocarcinoma Treatment ... #Rheumatology #