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diagnosis management apml cancer differential differentiation emergencies encephalopathy nephrology oncologic pres reversible sjogrens
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Overview What ... (renal potassium ... Rhabdomyolysis Treatment ... #pathophysiology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... viscosity > 4 cP • Associated ... Hyperuricemia • Acute renal ... failure • Hypocalcemia
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
(PRES) Overview ... may precede the neurologic ... fluctuations PRES-Associated ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... Anaphylaxis, Acute Renal ... diagnosis #management #hematology ... #oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Overview Epidemiology ... Primary form: not associated ... Distal (Type I) renal ... Adenocarcinoma Treatment ... #Rheumatology #
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