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management anemia leukemia aplastic behcet chronic classification cold dermatologic erythematosus gpa granulomatosis hemolytic hodgkins lupus lymphocytic mds monoclonal myelodysplasia paraproteinemias
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Syndrome (CAS): ... Viral Infection Clinical ... younger pts) Differential ... #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Easy or unusual bruising ... just beneath the skin ... #Syndromes #diagnosis ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... Alpha & Mu) Skin ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... ) Differential Diagnosis ... Ischemia, Leukemia, Lymphoma ... inhibitors • Uveitis- Ophthalmology ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Overview Epidemiology ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... • B cell lymphoma ... #Rheumatology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Causes: - Idiopathic ... (malignancy), lymphoma ... #diagnosis #dermatology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Overview Hodgkin's ... - Clinical Presentation ... ingestion • B symptoms ... number of sites of disease ... #hematology #oncology
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