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diagnosis oncology differential leukemia management chronic classification algorithm defects hemeonc hodgkins inherited lymphoma lymphomas lymphoproliferative mds myelodysplasia myelodysplastic nonhodgkin pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... - Summary Overview ... leukemia in adults • Disorder ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... lymphoproliferative disorders ... microglobulin Treatment ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Phosphorus CLL ... -> Invade Skin: ... transformation of the CLL ... #Leukemia #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders ... pathophysiology #Hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
biopsy demonstrates lymphocytes ... the mainstay of treatment ... hematopoietic stem cell ... Differential #Diagnosis #comparison ... #table #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Overview ... glands: • Focal lymphocytic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma Overview ... accounts for 10% of all ... • Autoimmune disorders ... Hodgkin Lymphoma Treatment ... classification #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... Neutropenia • Platelet Disorders ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology
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