6 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... inducers (↑) and inhibitors ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
clearance (calculated using ... interruption per treatment ... table ... direct thrombin inhibitor ... #pharmacology #
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#treatment #medications ... #table #pharmacotherapy ... #decisionaid #cardiology ... #hematology #warfarin ... #dosing
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Phosphodiesterase-4 (PDE4) Inhibitor ... Eosinophils < 100 Dosing ... : 250 mcg tablet ... recommendations for the treatment ... #Indications #Pharmacology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... Delivery • Stable ... Avoid ARBs • ICD ... diagnosis #management #cardiology ... #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
then be excreted using ... algorithm #management #cardiology ... #treatment #table ... #criticalcare #icu ... #clinical #pharmacology