40 results
Trends in Platelet Adenosine Diphosphate P2Y12 Receptor Inhibitor Use and Adherence Among Antiplatelet-Naive Patients After Percutaneous
Adenosine Diphosphate P2Y12 ... Cardiology #Adherence #Compliance ... #Clopidogrel #Prasugrel
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Clopidogrel to Prasugrel ... De-escalation in Potency: Prasugrel ... High Potency: Prasugrel ... Ticagrelor to Prasugrel ... antiplatelet #ticagrelor #prasugrel
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 ... anticoagulation in a-fib P2Y12 ... (clopidogrel, prasugrel ... - Inhibits the P2Y12
Antiplatelet Conversion - P2Y12 Inhibitor Switching
 • Clopidogrel (Plavix)
 • Prasugrel (Effient)
 • Ticagrelor (Brilinta)
Clopidogrel and
Antiplatelet Conversion - P2Y12 ... Clopidogrel (Plavix) • Prasugrel ... Clopidogrel and prasugrel ... active site of the P2Y12 ... Antiplatelet #Conversion #P2Y12
Oral P2Y12 Inhibitor Pharmacology

 • Clopidogrel
 • Prasugrel
 • Ticagrelor

By Kyle Fischer, PharmD @Kfischer_10

#P2Y12 #Inhibitor #Pharmacology
Oral P2Y12 Inhibitor ... Clopidogrel • Prasugrel ... Kfischer_10 #P2Y12
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors
A, Switching between oral agents in the acute/early phase.
Switching Between Oral P2Y12 ... escalating to prasugrel ... hours after last prasugrel ... ticagrelor to prasugrel ... CIRCULATIONAHA.117.031164 #P2Y12
External Ventricular Drains (EVDs) & ICP waveform interpretation
An EVD is a temporary closed sterile system that
CNS perfusion & compliance ... inversely to cerebral compliance ... ↑P2 with ↓compliance ... suggests abnormal CNS compliance ... markedly abnormal CNS compliance
COVID-19 Phenotypes - Implications for Respiratory Support Management

L Phenotype
 - Low Elastcnce (High Compliance)
 - Low
Elastcnce (High Compliance ... Elastance (Low Compliance
Ventilator Waveform Troubleshooting - High Peak Pressures

This OnePager explains how you can rapidly determine if High
Resistance Problem, a Compliance
If your PIP and Plateau are both elevated then this indicates lung disease and decreased compliance
and decreased compliance