23 results
hematology management differential signs oncology neurology vasculitis hemeonc hemophagocytic hlh leukemia lymphohistiocytosis psychiatry agglutinin aids algorithm anemia apml associated behavioraldisorder
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... common • Imaging: CXR ... : >3 symptoms, or ... : Infection (sepsis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (Cold-induced symptoms ... Diagnosis: • hemolytic ... hemolytic #anemia #hematology ... #diagnosis
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
- Differential Diagnosis ... papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... Matthew Ho, MD PhD
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
history of viral infection ... (Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs ... #differential #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... common infections ... management #treatment #hematology
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
failure with Reduced Ejection ... Typical symptoms ... Less Typical Symptoms ... of CXR congestion ... #management #cardiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... at the time of diagnosis ... e.g. incidental CXR ... #Management #Signs
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