11 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... organ-specific signs ... or symptoms (eg ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... pylori test (GI symptoms ... function test, ANA (e.g ... neurologic/psychiatric changes ... Causes #Workup #hematology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
) • Systemic symptoms ... and signs (e.g. ... lesion • CNS infection ... (e.g., meningitis ... Matthew Ho, MD PhD
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Romana's sign ... Indeterminate form (No signs ... /symptoms, positive ... 20-90%, normal ECG ... Cardiomyopathy: Conduction disorders
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... headaches, vision changes ... GCA #Temporal #Signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Malignancy (e.g ... . hematologic) ... (e.g. thyroid disease ... Induced Lupus: • Symptoms
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
and Signs: 50% ... mental status changes ... and signs: • ... leukocytosis, psychiatric disorders ... diagnostic procedures (eg
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Cardiac arrhythmias (e.g ... recent vision changes ... Peripheral neuropathy (e.g ... positive Romberg sign ... Joint instability (e.g
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
(e.g., EBV) ... and Symptoms: ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g