8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... common • Imaging: CXR ... Diagnosis: >3 symptoms ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... (e.g., meningitis ... Matthew Ho, MD PhD
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... of CXR congestion ... Jcortesizaguirr #HFrEF #heartfailure ... #diagnosis #management ... #cardiology #pharmacology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... of diagnosis (e.g ... . incidental CXR ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... GCA #Temporal #Signs ... #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
ECG is vital while ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment ... table #foamed #heartfailure
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Malignancy (e.g ... Endocrine disorders (e.g ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms