12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Prednisone 5mg/kg ... common • Imaging: CXR ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... • Serotonin syndrome ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... WBC >100k, + lab signs ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... • Visual inspection ... reservoir bag and APL ... obtain 12-lead ECG ... Checklist #Diagnosis #Management
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... • Visual inspection ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup #Cardiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Serologic and EMG ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... thoracotomy is a better treatment ... examination and vital signs ... Plan definitive management ... Checklist #Diagnosis #Management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... trolley, anaphylaxis treatment ... arrest, start CPR ... require prolonged treatment ... Checklist #Diagnosis #Management
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Symptoms and Signs ... common symptoms and signs ... diagnostic procedures (eg ... colonoscopy), induction ... of anesthesia,
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... JVD, Orthopnea/PND ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment