10 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
weakness in: 1. ... Serologic and EMG ... Findings: 1. ... - Peek sign ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... symptoms, or> 1 ... APML #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... Treatment of GCA ... them, but urgent rheumatology ... GCA #Temporal #Signs ... Symptoms #Diagnosis #Management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... of infections) ... • IVIg 2 g/kg/month ... #diagnosis #management ... #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... TNF blockers had ... efficacious include IL-1 ... #Rheumatology # ... diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL-1 ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Spontaneous Bacterial Peritonitis
DIAGNOSTICS
Paracentesis: 
 • Calculate absolute PMN count (total WBC x PMN %)
 • Correct
Treat if other signs ... 1: 1.5 g/kg of ... ↓ rebleeding, infections ... SBP #diagnosis #management ... #prophylaxis #treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
typically fall into 1 ... Signs of congestion ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... positive patients Treatment ... mg/kg per day • ... #diagnosis #management ... #rheumatology #
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... to Manifest: 1. ... sex • Metabolic syndrome ... in a year • 1 ... #treatment #rheumatology