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diagnosis management hematology algorithm differential blood vasculitis acr2021 activation antinxp2 antinxp2dm bacterial brain cardiomyopathy clinical crypto cryptococcal dermatology dermatomyositis disorders
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... syndrome, POEMS • Reaction ... Matthew Ho, MD PhD
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Guidelines • Severe Disease ... • Non-Severe Disease ... immunosuppressive agent (e.g ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Graft Versus Host Disease ... RBCs (stored at 4C ... Borrellia (Lyme disease ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
FNHTR once had ... Blood products contain ... Infection - Infection ... RBCs (stored at 4C ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(eg, systemic juvenile ... SLE], AOSD) • Infection ... Fibrin degradation products ... Treatment: • Corticosteroids ... #Rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Valvular heart disease ... exertion, orthopnea, PND ... Avoid estrogen products ... diagnosis #management #cardiology ... #treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, drug reactions ... to exclude are infections ... purpura: Strong sign ... Polyarteritis Nodosa: • PAN ... Differential #Diagnosis #Rheumatology
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
Treat if other signs ... 1: 1.5 g/kg of ... ↓ rebleeding, infections ... advanced liver disease ... #prophylaxis #treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... antibody positive had ... more severe disease ... positive patients Treatment ... diagnosis #management #rheumatology
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