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diagnosis hematology management oncology algorithm antinxp2 antinxp2dm chronic cll dermatomyositis differential differentiation disorders eosinophil eosinophilia leukemia lymphocytic syndrome workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... Renal Failure Treatment ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
drug reaction, infection ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Physical Exam/Signs ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... antibody positive had ... positive patients Treatment ... diagnosis #management #rheumatology ... #dermatology
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