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diagnosis hepatology alkaline alp biliary bilirubinemia cirrhosis classification conjugated elevation phosphatase unconjugated workup
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
miscellaneous causes ... mononucleosis, cholangitis ... duct, sclerosing cholangitis ... #unconjugated #differential ... #causes
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Cholangiocarcinoma • Primary ... Sclerosing Cholangitis ... #Jaundice #Differential ... #Causes #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... slightly elevated • Bilirubin ... bile ducts Differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis
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