21 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... turnover • Acute ... • Hemolytic anemia ... Splenomegaly, Sickle Cell ... End-stage renal disease
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... extramedullary disease ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
disease - an autosomal ... Sickle cell disease ... 2) Aplasia - Acute ... of the baseline anaemia ... Crisis #Features #Signs
Shock - Diagnosis and Management Summary
 • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Diagnosis and Management ... Full Set of Vital Signs ... support - Call ... - Pulmonary >> Acute ... #Summary #criticalcare
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Fever Hematologic disease ... caused by Bartonella ... anorexia, ARDS ​• RBC ... severe hemolytic anemia ... Fever #diagnosis #management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... Send for cell count ... Inflammatory, crystalline disease ... Like in this case ... rheumatology #approach #workup
Clinical Management for Three Common Causes of Shock 
HEMORRHAGIC SHOCK
 • Ensure adequate ventilation and oxygenation.
Clinical Management ... for Three Common Causes ... packed red blood cell ... #Shock #Management ... #CriticalCare
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
is unconscious, signs ... ischaemia ❶ Call ... calcium. ❽ Treat anaemia ... Checklist #Diagnosis #Management ... #Workup