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diagnosis differential management algorithm causes classification leukemia approach arthritis calculation chronic cll crisis dermatology disease disorders features hodgkins index laboratory
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Loss • Acute ... Deficiency • Aplastic ... Anemia • Anemia ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... result from low blood ... #Anemia #oncology ... #hematology #diagnosis
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
the peripheral blood ... marrow failure: Aplastic ... Index > 3: • Acute ... blood loss: Trauma ... Production #Index #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... changes), high MCV anemia ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... Pure red cell aplasia ... ’s lymphoma or acute ... #oncology #hematology
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
with severe pain, lasting ... ischaemia. 2) Aplasia ... - Acute worsening ... of the baseline anaemia ... Crisis #Features #Signs
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... - Acute Hemolytic ... Transfusion Related Acute ... due to marrow aplasia ... diagnosis #management #hematology
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