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diagnosis rheumatology arthritis differential leukemia msk pain systemic approach cll dermatology disease erythematosus gout laboratory lupus lymphocytic management mds monoarthritis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronicity: • Acute ... rheumatic fever • Chronic ... hepatitis, herpes • Chronic ... #rheumatology # ... approach #workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic: PBC ... Musculoskeletal: joint ... #diagnosis #signs ... #symptoms #testing ... #workup
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
, erythema and WBC ... the time course (acute ... noninflammatory Signs ... Morning stiffness lasting ... Diagnosis #MSK #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... Screening Tests for Chronic ... Arthritis #laboratory #workup
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... attacks • Other joints ... Synovial Fluid Testing ... double contour sign ... +Radiographic signs
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Episcleritis Signs ... , breast CA - Hematologic ... - CBC may also ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Arthritis: • Joint ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
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