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diagnosis differential hematology joint leukemia msk pain algorithm approach causes classification cll diffuse disease erythematosus gap globulin laboratory lupus lymphadenopathy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Rheumatoid Arthritis ... Fatigue • Acute ... Age > 50 • Chronic ... Lymphadenopathy #LAD ... #Oncology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... If that patient had ... hepatitis, herpes • Chronic ... Joint #Pain #MSK #rheumatology ... #approach #workup
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
, erythema and WBC ... the time course (acute ... noninflammatory Signs ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... Screening Tests for Chronic ... #laboratory #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... compounds, alcohol, lead ... Workup: • Complete ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... purpura: strong sign ... retinopathy Lab ... Tests: • CBC ... differential #diagnosis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Viral infections (acute ... (RA, Temporal arteritis ... Thalassemia, Sickle cell anemia ... inflammation (acute
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