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diagnosis hematology differential lymphocytic management algorithm causes chronic mds pathophysiology rheumatology syndrome arthritis atlas bandemia cancer cbc classification crisis dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... treatment #hematology #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... , Myelodysplastic ... cells - Sickle cell ... Malignant tumors, Acute
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Leukemia • Idiopathic ... Myeloproliferative Disease ... Workup: • Complete ... diagnosis #hematology #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... marrow failure with anemia ... #oncology #hematology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
usually in the setting ... of autoimmune disease ... Neutropenia (85%), anemia ... presentation (PB ... morphologic/clinical disease
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... PT, aPTT(liver disease ... changes), high MCV anemia ... not required in all
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... Tissue damage • Leukemia ... • Autoimmune diseases ... especially in the setting
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