2 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... initiation • Differential ... Infection (sepsis), PE ... fluid overload, PCC ... #diagnosis #management
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Acute Diarrhea (>3 BM ... immunocompromised, IBD) • ↑Risk ... Lowest Risk: Tetracyclines ... non-toxigenic • Stool PCR ... Bezlotoxumab 10 mg/kg