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diagnosis differential management infections infectiousdiseases 1 agglutinin aids anemia brain cdi cdiff cell clostridioides clostridium cold difficile disease encephalitis gastroenterology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
CNS Ring-Enhancing ... PCR 50% sensitive ... granulomatosis: • EBV-associated ... differential #diagnosis #causes ... #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
hemorrhage • CSF PCR ... Toxoplasma gondii PCR ... • JC-virus PCR ... effect/Edema • EBV ... Enhancement • PCR
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
OnePager Summary Autoimmune ... antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... diagnosis #management #treatment
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... Agglutinin Syndrome (CAS ... Viral infection, autoimmune ... - Mycoplasma, EBV ... Hemoglobinuria (PCH
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
disorder (Cardiac, pulmonary ... PNS -> NMJ -> Muscle ... necrotizing myopathy • Autoimmune ... Coxsackie, HIV, CMV, EBV ... cryoglobulins • PNS
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Encephalitis: MCC ... Enteroviruses (e.g ... virus • CMV • EBV ... Singh @rav7ks #CNS
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... Antibiotics (Bactrim, PCN ... only if no clear cause ... Bicarb<22) - avoid NS ... #potassium #nephrology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
of hospitalized pts ... Acute Diarrhea (>3 BM ... non-toxigenic • Stool PCR ... Bezlotoxumab 10 mg/kg ... IDSA 2021 CDI Treatment
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... • ANA < 20 % IBM ... aspiration > 50% of pts ... statins - probably caused ... Other Diseases: • PBC
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
inflammatory or autoimmune ... • Pulmonary Symptoms ... CNS involvement: ... Birbeck granules (EM ... TREATMENT OPTIONS
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