9 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... Iron deficiency anemia ... #Differential #Diagnosis ... #Algorithm #causes
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... • Symptoms of anemia ... anemia • Cold ... #hemolytic #anemia ... #hematology #diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... guidelines General - Systemic ... #Limping #NWB #Algorithm ... #Child #Peds #Pediatrics ... #Diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... • CAD APLA/LAC ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Algorithm Hypertension ... Renal Parenchymal Diseases ... syndrome • AKI/CKD ... Sympathetic nervous system ... HTN #Secondary #Nephrology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... cells can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... workup #oncology #hematology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
function of multiple systems ... embolism - Severe anemia ... Auditory/Vestibular System ... Recurrent #Falls #Diagnosis ... #Neurology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
- differential diagnosis ... pruritus • Hematologic ... Iron deficiency anemia ... #Management #Nephrology ... #CKD