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Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
- Emergency Causes ... cord infarct • HIV ... Tethered cord • Guillain-Barre ... Imaging studies: • MRI ... decompression #CaudaEquina
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Causes: • Large ... suspected, immediate MRI ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... #diagnosis #symptoms
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Campylobacter jejuni - HIV ... Diagnosis: • ... axonal form • MRI
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... immunodeficiency virus (HIV ... and sensitive tests ... the underlying pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... NMO-IgG (anti-AQP4) should ... negative, MOG-IgG test ... should be ordered ... simplex virus, HIV
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... The evaluation should ... II ○ Susac’s syndrome ... Noise trauma ○ MS ... zoster virus ○ HIV
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... glucose suppression test ... • Pituitary MRI ... or refractory cases